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Expanding transglial wave in the intact cerebellum triggerred by ATP.

Expanding transglial wave in the intact cerebellum triggerred by ATP.

The cerebellum was bolus-loaded with OGB-1/AM and ATP was ejected through a pipette co-loaded with Alexa 594 to trigger a transglial calcium wave. The ellipsoid shape of triggered waves was similar to those occurring spontaneously. This is probably caused by the dense packing of parallel fibers, which favors transverse over sagittal diffusion.

Keywords: ATP, Bergmann glia, Alexa, Cerebellum, OGB-1

Posted by: Tycho Hoogland

Posted on: 15 Oct 2013

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