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Hexabromocyclododecane (HBCD or HBCDD) and PPAR-a knockout mice

Hexabromocyclododecane (HBCD or HBCDD) and PPAR-a knockout mice

PPAR-alpha knock-out mice were treatead with HBCD for 10 days. The treatment was administrated dayly with fodder in three different doses 2,4 and 10 mg/Kg-bw. The mice were sacrificied by cervical dislocation and the liver and kidney dissected for analysis.

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Toxicogenomics