Event Abstract

Clinical applications of bidirectional brain-machine interfaces

  • 1 University of Washington, Department of Physiology and Biophysics, United States

Bidirectional brain-machine interfaces (BBMI) have recurrent connections that allow activity-dependent stimulation of the brain, spinal cord or muscles. Such BBMIs operating continuously during free behavior have three major applications for basic research and clinical rehabilitation. First, the brain could learn to incorporate a long-term artificial recurrent connection into normal behavior, exploiting its ability to adapt to consistent sensorimotor conditions. In clinical applications an artificial recurrent connection could be used to bridge a lost biological connection. Second, activity-dependent stimulation can generate synaptic plasticity on the cellular level. The corresponding clinical application is to strengthen weakened neural connections, such as occurs in stroke. A third application involves delivery of activity-dependent stimulation at subcortical reward sites, which can operantly reinforce the activity that generates the stimulation. The BBMI paradigm has numerous specific applications, depending on the source of the signals and the stimulated targets.

Conference: 2015 International Workshop on Clinical Brain-Machine Interfaces (CBMI2015), Tokyo, Japan, 13 Mar - 15 Mar, 2015.

Presentation Type: Oral presentation / lecture

Topic: Clinical Brain-Machine Interfaces

Citation: Fetz E (2015). Clinical applications of bidirectional brain-machine interfaces. Conference Abstract: 2015 International Workshop on Clinical Brain-Machine Interfaces (CBMI2015). doi: 10.3389/conf.fnhum.2015.218.00030

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Received: 23 Apr 2015; Published Online: 29 Apr 2015.

* Correspondence: PhD. Eberhard Fetz, University of Washington, Department of Physiology and Biophysics, Seattle, WA, 98195, United States, fetz@uw.edu