New Height, Weight and Head
Circumference Charts for
Children with Williams Syndrome
in the United Kingdom
-
1
East Kent Hospitals NHS Trust, United Kingdom
-
2
UCL Institute of Child Health, United Kingdom
Aim: To produce a growth reference for children in the UK with Williams syndrome.
Method: The children and adults were all affiliated to the Williams Syndrome Foundation a parent support group founded in 1979. They have all been shown to have a deletion of chromosome 7q,11,23. Prospective measurements were made by one growth nurse (WRS) from 19 regions in the UK, including Scotland, England and Wales. 176 children and adults were measured on up to 4 occasions between 2001 and 2004 (635 measurements). In addition retrospective data was obtained from the hospital notes of 67 of these same individuals (333 measurements). Centile curves were constructed using Cole’s LMS method (1).
Results: The centile charts differ from charts previously derived in the USA and Germany and provide more appropriate standards for the UK population (2,3).
Conclusions: We propose that these charts be adopted for routine clinical practice as abnormalities in growth are an important feature of this syndrome.
Conference:
12th International Professional Conference on Williams Syndrome, Garden Grove,CA, United States, 13 Jul - 14 Jul, 2008.
Presentation Type:
Poster Presentation
Topic:
Multidisciplinary Poster Session
Citation:
Martin
ND,
Smith
WR,
Preece
MA and
Cole
TJ
(2009). New Height, Weight and Head
Circumference Charts for
Children with Williams Syndrome
in the United Kingdom.
Conference Abstract:
12th International Professional Conference on Williams Syndrome.
doi: 10.3389/conf.neuro.09.2009.07.051
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Received:
04 May 2009;
Published Online:
04 May 2009.
*
Correspondence:
W. R Smith, East Kent Hospitals NHS Trust, Kent, United Kingdom, wendy.aquajoy@btinternet.com