Neural generators of the auditory P3a and P3b revealed by ERPs and LORETA
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1
Jagiellonian University, Poland
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2
Radboud University, Netherlands
There is agreement that P300 is not a unitary brain potential but represents the summation of activity from various widely distributed areas in the brain. The distinction can be made between two subcomponents obtained within P300 time window, namely P3a and P3b. There is evidence that these components differ in their scalp topography, latency and reflect different sets of processes. It was previously suggested that P3a with a frontocentral distribution reflects an initial involuntary attention engagement in the frontal lobe. The P3b has a parietal maximum and could be assigned to voluntary event classification in tasks that require covert or overt response to stimuli. These findings were supported by recent lesion studies as well as neuroimaging or intracranial recordings in humans. However, the neural generators of these components are still not completely described. We recorded ERPs to auditory stimuli in the three-stimulus oddball task. The magnitude of P3a response to non-target deviants was found bigger in comparison to targets. Both revealed frontal-central maxima. In contrast to this, we obtained larger P3b response to targets when compared to non-targets. Maxima of these responses we obtained at posterior sites. These effects were also tested with Low Resolution Electromagnetic Tomography (LORETA). We found that P3a response could be related to activity within cingulate cortex and adjacent medial portion of frontal lobe. The P3b response can be connected with activity located in posterior part of cingulate gyri and precuneus. Our results support the thesis that P3a and P3b reflect distinct psychological and physiological processes generated in different brain regions.
Conference:
10th International Conference on Cognitive Neuroscience, Bodrum, Türkiye, 1 Sep - 5 Sep, 2008.
Presentation Type:
Poster Presentation
Topic:
Decision Making and Response Selection
Citation:
Wronka
E,
Kaiser
J and
Coenen
A
(2008). Neural generators of the auditory P3a and P3b revealed by ERPs and LORETA.
Conference Abstract:
10th International Conference on Cognitive Neuroscience.
doi: 10.3389/conf.neuro.09.2009.01.217
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Received:
08 Dec 2008;
Published Online:
08 Dec 2008.
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Correspondence:
Eligiusz Wronka, Jagiellonian University, Cracow, Poland, eligiusz.wronka@gmail.com