CLINICAL NUTRITION PROGRAM IMPROVES SENSORY LOSS IN A 60 YEAR OLD TRUCK DRIVER WITH ANTI-MAG NEUROPATHY
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1
Carrick Institute of Clinical Neuroscience and Rehabilitation, United States
Background:
A 60 year old man presented with chief complaints of fatigue, weakness in the legs and difficulty walking secondary to anti-MAG associated neuropathy diagnosed one year prior to presentation. He also noted decreased sensation in the feet, general stiffness in the legs, occasionally stiffness in the hands, as well as near constant tingling in the hands. Intravenous Immunoglobulin therapy had been recommended, but the patient refused that treatment. He had adopted a gluten-free diet two months prior to presentation and was taking fish oil, glucosamine, licorice root, alpha lipoic acid and arginine.
Methods:
Neurological examination revealed hair loss on the legs up to the level of the knee on both legs, lateropulsion to the right and reduced arm swing bilateral and slowed gait with dual tasking of gait, adequate muscle strength in the upper and lower extremities, hypoactive muscle stretch responses at the patella and ankle on both lower limbs, loss of vibration sensation on the right leg from the foot up to the level of the patella, loss of vibration sensation on the left great toe, abnormal heel to shin testing on the right leg, and increases latency of upwards, rightwards and leftward saccades.
Blood chemistry revealed high glucose (114), high Hemoglobin A1c (6.0), high calcitriol (132), low absolute lymphocytes (0.5) and clinically significant results as follows: homocysteine (12.9), vitamin D (36.7), white blood cell count (3.7), neutrophil percentage (80).
He was directed to stop his current supplementation and was placed on an anti-inflammatory diet and supplement regimen including vitamin D, omega fatty acids, turmeric, resveratrol, and broad spectrum multivitamin/multimineral formula containing therapeutic amounts of chromium and vanadium.
Results:
After 30 days of treatment, vibration sensation had improved and was now intact on the right leg at the level of the patella and medial malleolus. Dual tasking gait did not elicit lateropulsion and arm swing was normal. Muscle stretch responses at the patella and ankle remained hyporeflexive.
After 60 days of treatment, vibration sensation was intact at the right first toe. Saccade latencies were normal, but asymmetrical.
Over the next six months, he maintained the improvements. He discontinued the turmeric and resveratrol and continued to maintain the same level of improvement. He passed the yearly physical required to maintain his truck driving license. One year after presentation, the physician who diagnosed him with the anti-MAG neuropathy noted that the neuropathy had failed to progress.
Conclusion:
The author suggests further investigation into clinical nutrition and supplementation in the treatment of patients with anti-MAG neuropathy.
Keywords:
Anti-MAG neuropathy,
Sensory loss,
Immune-mediated neuropathy,
Anti-inflammatory diet,
gluten-free casein-free diet
Conference:
International Symposium on Clinical Neuroscience: Clinical Neuroscience for Optimization of Human Function, Orlando, United States, 7 Oct - 9 Oct, 2016.
Presentation Type:
Poster Presentation
Topic:
Abstracts ISCN 2016
Citation:
Clark
DJ
(2016). CLINICAL NUTRITION PROGRAM IMPROVES SENSORY LOSS IN A 60 YEAR OLD TRUCK DRIVER WITH ANTI-MAG NEUROPATHY
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Front. Neurol.
Conference Abstract:
International Symposium on Clinical Neuroscience: Clinical Neuroscience for Optimization of Human Function.
doi: 10.3389/conf.fneur.2016.59.00091
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Received:
02 Sep 2016;
Published Online:
07 Sep 2016.
*
Correspondence:
Dr. David J Clark, Carrick Institute of Clinical Neuroscience and Rehabilitation, Cape Canaveral, FL, United States, mail@doctordavidclark.com